El Hotel Nube está ubicado en el centro de la ciudad de Puebla, a cinco cuadras de la Catedral y del Palacio Municipal, también se encuentra a unos cuantos minutos de interesantes atractivos turísticos, como son la Capilla del Rosario, la Casa del Alfeñique, la Biblioteca Palafoxiana, el mercado de artesanías el Parián y el Centro de convenciones. A una cuadra se encuentra la Av. 5 de mayo donde hay varias paradas de autobús y sitios de taxi.
Av. 4 Oriente #407
Col. Centro Puebla, Pue. México 72000
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